I beseech the developer community to swear to never use #region or #endregion blocks again, except for possibly machine generated code.

The first step is to stop typing #region and #endregion. This will greatly improve the transparency of your code. Next, because you are the sort of person that uses #region and #endregion to hide the code you are ashamed of– go find all those HACK:, BUG:, and CRAP: comments.